Dihydrolipoic Acid

Dihydrolipoic acid (DHLA) is a dithiol-containing carboxylic acid that is the reduced form of alpha-lipoic acid (Cay-10005728). It acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including hydroxyl radicals, peroxynitirite, hydrogen peroxide, and hypochlorite, at concentrations ranging from 0.01-0.5 mM. At concentrations of 50-100 µM, DHLA triggers apoptosis of mouse embryonic stem cells and human cancer cells, suppressing proliferation.Formal Name: 6,8-dimercapto-octanoic acid. CAS Number: 462-20-4. Synonyms: DHLA. Molecular Formula: C8H16O2S2. Formula Weight: 208.3. Purity: >95%. Formulation: (Request formulation change), A neat oil. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2) (1:8): 0.25 mg/ml. SMILES: OC(CCCCC(S)CCS)=O. InChi Code: InChI=1S/C8H16O2S2/c9-8(10)4-2-1-3-7(12)5-6-11/h7,11-12H,1-6H2,(H,9,10). InChi Key: IZFHEQBZOYJLPK-UHFFFAOYSA-N.