DC4 Crosslinker

DC4 crosslinker is a mass spectrometry-cleavable crosslinking reagent (18Å in length) that contains two intrinsic positive charges, which allow cross-linked peptides to fragment into their component peptides by collision-induced dissociation or in-source decay. Initial fragmentation events result in cleavage on either side of the positive charges so that cross-linked peptides can be identified as pairs of ions separated by defined masses. Additionally, these two intact peptide fragments can be further fragmented to yield a series of b- and y-ions for peptide identification.Formal Name: 1,4-bis[4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl]-1,4-diazoniabicyclo[2.2.2]octane, dibromide. CAS Number: 1374647-94-5. Molecular Formula: C22H32N4O8 . 2Br. Formula Weight: 640.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 11 mg/ml, PBS (pH 7.2): 3 mg/ml. SMILES: O=C(ON1C(CCC1=O)=O)CCC[N+]23CC[N+](CC3)(CCCC(ON4C(CCC4=O)=O)=O)CC2.[Br-].[Br-]. InChi Code: InChI=1S/C22H32N4O8.2BrH/c27-17-5-6-18(28)23(17)33-21(31)3-1-9-25-11-14-26(15-12-25,16-13-25)10-2-4-22(32)34-24-19(29)7-8-20(24)30,,/h1-16H2,2*1H/q+2,,/p-2. InChi Key: AJWAJFDEYIAPKX-UHFFFAOYSA-L.