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D13 is an acylhydrazone antifungal. It is active against C. neoformans in vitro (MIC80 = 0.06 µg/ml). D13 (20 mg/kg per day, p.o.) increases survival in mouse models of C. neoformans, C. albicans, or A. fumigatus infection.Formal Name: 4-bromo-benzoic acid, 2-[(3,5-dibromo-2-hydroxyphenyl)methylene]hydrazide. CAS Number: 321945-27-1. Molecular Formula: C14H9Br3N2O2. Formula Weight: 476.9. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 10 mg/ml. lambdamax: 244, 295, 307, 341 nm. SMILES: O=C(N/N=C/C1=CC(Br)=CC(Br)=C1O)C2=CC=C(Br)C=C2. InChi Code: InChI=1S/C14H9Br3N2O2/c15-10-3-1-8(2-4-10)14(21)19-18-7-9-5-11(16)6-12(17)13(9)20/h1-7,20H,(H,19,21)/b18-7+. InChi Key: QERLWOMVFDBAFP-CNHKJKLMSA-N.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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