D-myo-Inositol-1,2,4,5-tetraphosphate (sodium salt)

D-myo-Inositol-1,2,4,5-tetraphosphate (Ins(1,2,4,5)P4) is one of the many inositol phosphate (InsP) isomers that act as small, soluble second messengers in the transmission of cellular signals. Ins(1,2,4,5)P4 exhibits agonist activity at the Ins(1,4,5)P3 receptor expressed in CHO cells where it induces Ca2+ mobilization with an ED50 value of 0.22 µM, making it nearly equipotent to Ins(1,4,5)P3 (EC50 = 0.1 µM) in the same assay.Formal Name: D-myo-inositol-1,2,4,5-tetrakis(dihydrogen phosphate), tetrasodium salt. Synonyms: Ins(1,2,4,5)P4, 1,2,4,5-IP4. Molecular Formula: C6H12O18P4. 4Na. Formula Weight: 588.0. Purity: >98%. Formulation: (Request formulation change), A lyophilized powder. Solubility: Water: 50 mg/ml. SMILES: O[C@@H]1[C@@H](OP([O-])(O)=O)[C@H](OP([O-])(O)=O)[C@@H](O)[C@@H](OP([O-])(O)=O)[C@H]1OP([O-])(O)=O.[Na+].[Na+].[Na+].[Na+]. InChi Code: InChI=1S/C6H16O18P4.4Na/c7-1-3(21-25(9,10)11)5(23-27(15,16)17)2(8)6(24-28(18,19)20)4(1)22-26(12,13)14,,,,/h1-8H,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20),,,,/q,4*+1/p-4/t1-,2-,3?,4?,5?,6?,,,,. InChi Key: GPEDWSWFXATPAL-ZGXJPNOWSA-J.