(D)2-Rh 110 (trifluoroacetate salt)

(D)2-Rh 110 is a fluorogenic caspase substrate. Upon enzymatic cleavage by caspases, rhodamine 110 (Cay-19061) is released in an apoptosis-dependent manner and its fluorescence can be used to quantify caspase activity. Rhodamine 110 displays excitation/emission maxima of 496/520 nm, respectively.Formal Name: (3S,3'S)-4,4'-[(3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl)diimino]bis[3-amino-4-oxo-butanoic acid, trifluoroacetate salt. Synonyms: D2R, (Asp)2-Rhodamine 110, Rhodamine 110 bis-(L-aspartic acid amide). Molecular Formula: C28H24N4O9 . XCF3COOH. Formula Weight: 560.5. Purity: >95%. Emission: 520 nm. Excitation: 496 nm. Formulation: (Request formulation change), A solid. Solubility: Formic Acid: 1 mg/ml. SMILES: O=C([C@@H](N)CC(O)=O)NC1=CC=C(C2(C(C=CC=C3)=C3C(O2)=O)C(C=CC(NC([C@@H](N)CC(O)=O)=O)=C4)=C4O5)C5=C1.OC(C(F)(F)F)=O. InChi Code: InChI=1S/C28H24N4O9.C2HF3O2/c29-19(11-23(33)34)25(37)31-13-5-7-17-21(9-13)40-22-10-14(32-26(38)20(30)12-24(35)36)6-8-18(22)28(17)16-4-2-1-3-15(16)27(39)41-28,3-2(4,5)1(6)7/h1-10,19-20H,11-12,29-30H2,(H,31,37)(H,32,38)(H,33,34)(H,35,36),(H,6,7)/t19-,20-,/m0./s1. InChi Key: KIHCZYKJFWQUGV-FKLPMGAJSA-N.