Cyclic GMP (sodium salt)

Cyclic GMP (cGMP) is a second messenger that is biosynthesized from GTP by guanylate cyclases. Activators of guanylate cyclases include nitric oxide and natriuretic peptides. cGMP activates protein kinase G (PKG) and modulates ion channel conductance, with signaling affecting diverse processes including smooth muscle relaxation and proliferation, phototransduction, and energy homeostasis. The degradation of cGMP to GMP is mediated by specific and non-specific phosphodiesterases.Formal Name: cyclic 3',5'-(hydrogen phosphate) guanosine, monosodium salt. CAS Number: 40732-48-7. Synonyms: cGMP, Cyclic guanosine monophosphate, Guanosine 3'5'-cyclic monophosphate, Monosodium-GMP. Molecular Formula: C10H11N5O7P . Na. Formula Weight: 367.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: Water: Slightly Soluble. lambdamax: 256 nm. SMILES: O[C@H]1[C@H](N2C=NC3=C2N=C(N)NC3=O)O[C@@]4([H])[C@@]1([H])OP(OC4)([O-])=O.[Na+]. InChi Code: InChI=1S/C10H12N5O7P.Na/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6,/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17),/q,+1/p-1/t3-,5-,6-,9-,/m1./s1. InChi Key: KMPIYXNEROUNOG-GWTDSMLYSA-M.