CAY10762

CAY10762 is an inhibitor of monoacylglycerol lipase (MAGL, IC50 = 34.1 nM). It reduces hydrogen peroxide-induced lactate dehydrogenase (LDH) release from Neuro2a cells when used at a concentration of 1 µM. CAY10762 (10 mg/kg) increases levels of 2-arachidonoyl glycerol (2-AG, Cay-62160) in mouse brain.Formal Name: 2-(2-phenylethyl)-1,2-benzisothiazol-3(2H)-one. CAS Number: 2514-37-6. Molecular Formula: C15H13NOS. Formula Weight: 255.3. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 15 mg/ml, DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml, DMSO: 10 mg/ml, Ethanol: 1 mg/ml. lambdamax: 227, 247 nm. SMILES: O=C1C2=CC=CC=C2SN1CCC3=CC=CC=C3. InChi Code: InChI=1S/C15H13NOS/c17-15-13-8-4-5-9-14(13)18-16(15)11-10-12-6-2-1-3-7-12/h1-9H,10-11H2. InChi Key: VUMUTUGUKRGYGW-UHFFFAOYSA-N.