CAY10669

CAY10669 is an inhibitor of the histone acetyltransferase PCAF (p300/CREB-binding protein-associated factor, IC50 = 662 µM), displaying a 2-fold improvement in inhibitory potency over anacardic acid (Cay-13144). At 30-60 µM, CAY10669 can dose-dependently inhibit histone H4 acetylation in HepG2 cells in vitro.Formal Name: 2-hydroxy-6-[(1Z)-2-[4-(pentyloxy)phenyl]ethenyl]-benzoic acid. CAS Number: 1243583-88-1. Molecular Formula: C20H22O4. Formula Weight: 326.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml. lambdamax: 327 nm. SMILES: OC1=CC=CC(/C=C\C2=CC=C(OCCCCC)C=C2)=C1C(O)=O. InChi Code: InChI=1S/C20H22O4/c1-2-3-4-14-24-17-12-9-15(10-13-17)8-11-16-6-5-7-18(21)19(16)20(22)23/h5-13,21H,2-4,14H2,1H3,(H,22,23)/b11-8-. InChi Key: JZTUSBQKQHUSQE-FLIBITNWSA-N.