CAY10616

Resveratrol is a natural polyphenolic antioxidant that has anti-cancer properties. CAY10616 is an analog of resveratrol which potently induces apoptosis in promyelocytic leukemia HL-60 cells (IC50 = 40 nM, vs. 50 µM for resveratrol). In addition, CAY10599 induces apoptosis (IC50 = 30 nM) in HL-60R, a cell line derived from HL-60 that expresses a multidrug-resistance phenotype (resistant to daunorubicin, etoposide, and citarabine).Formal Name: 5-[(1Z)-2-(3,5-dimethoxyphenyl)ethenyl]-2-methoxy-phenol. CAS Number: 586410-08-4. Molecular Formula: C17H18O4. Formula Weight: 286.3. Purity: >98%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: 20 mg/ml, DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml, DMSO: 14 mg/ml, Ethanol: 10 mg/ml. lambdamax: 291 nm. SMILES: COc1cc(\C=C\c2ccc(OC)c(O)c2)cc(OC)c1. InChi Code: InChI=1S/C17H18O4/c1-19-14-8-13(9-15(11-14)20-2)5-4-12-6-7-17(21-3)16(18)10-12/h4-11,18H,1-3H3/b5-4-. InChi Key: UQIWTPQGJCCTPA-PLNGDYQASA-N.