Carnosic Acid

Carnosic acid is an active diterpene found in rosemary (R. officinalis) and common sage (S. officinalis). Its antioxidant properties include inhibition of lipid peroxidation and scavenging of peroxyl radicals. Carnosic acid has been shown to be cytotoxic towards various human cancer cell lines, reducing cell viability to 13-30% 48 hours after application at a concentration of 6.25 µg/ml.Formal Name: 1,3,4,9,10,10aS-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-4aR(2H)-phenanthrenecarboxylic acid. CAS Number: 3650-09-7. Synonyms: Salvin. Molecular Formula: C20H28O4. Formula Weight: 332.4. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml. lambdamax: 284 nm. SMILES: OC1=C([C@]2(C(O)=O)C(CC3)C(C)(C)CCC2)C3=CC(C(C)C)=C1O. InChi Code: InChI=1S/C20H28O4/c1-11(2)13-10-12-6-7-14-19(3,4)8-5-9-20(14,18(23)24)15(12)17(22)16(13)21/h10-11,14,21-22H,5-9H2,1-4H3,(H,23,24). InChi Key: QRYRORQUOLYVBU-UHFFFAOYSA-N.