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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay10010681-1 | 1 mg | - |
6 - 10 business days* |
401.00€
|
|||
Cay10010681-5 | 5 mg | - |
6 - 10 business days* |
797.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Capecitabine-d11 is intended for use as an internal standard for the quantification of... more
Product information "Capecitabine-d11"
Capecitabine-d11 is intended for use as an internal standard for the quantification of capecitabine (Cay-10487) by GC- or LC-MS. Capecitabine is a prodrug form of 5-fluorouracil (5-FU, Cay-14416). It is converted to 5-FU via several enzymatic steps beginning in the liver and ending with conversion in tumor tissue by thymidine phosphorylase, an enzyme that is more concentrated in tumor tissue compared with normal tissue. Capecitabine is cytotoxic only at high concentrations in Scaber, SIHA, and MKN45 cells (IC50s = 97, 578, and 994 µM, respectively) and is inactive in a variety of cancer cell lines, including COLO 205, HCT116, and MCF-7 cells (IC50s = >1,000 µM).Formal Name: 5'-deoxy-5-fluoro-N-[(pentyl-1,1,2,2,3,3,4,4,5,5,5-d11-oxy)carbonyl]-cytidine. CAS Number: 1132662-08-8. Molecular Formula: C15H11D11FN3O6. Formula Weight: 370.4. Purity: >99% deuterated forms (d1-d11). Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: Slightly Soluble, Methanol: Warmed. SMILES: CCCCCOC(=O)Nc1nc(=O)n(cc1F)[C@@H]1O[C@H](C)C(O)C1O. InChi Code: InChI=1S/C15H22FN3O6/c1-3-4-5-6-24-15(23)18-12-9(16)7-19(14(22)17-12)13-11(21)10(20)8(2)25-13/h7-8,10-11,13,20-21H,3-6H2,1-2H3,(H,17,18,22,23)/t8-,10-,11-,13-/m1/s1/i1D3,3D2,4D2,5D2,6D2. InChi Key: GAGWJHPBXLXJQN-XSFNBKHLSA-N.
Keywords: | 5'-deoxy-5-fluoro-N-[(pentyl-1,1,2,2,3,3,4,4,5,5,5-d11-oxy)carbonyl]-cytidine |
Supplier: | Cayman Chemical |
Supplier-Nr: | 10010681 |
Properties
Application: | DNA synthesis inhibitor |
MW: | 370.4 D |
Formula: | C15H11D11FN3O6 |
Purity: | >99% deuterated forms (d1-d11) |
Format: | Crystalline Solid |
Database Information
CAS : | 1132662-08-8| Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
|
H Phrases: | H341, H350, H360, H402 |
P Phrases: | P201, P202, P273, P280, P308+313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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