Camostat (mesylate)

Camostat (mesylate)
COVID-19 Research
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay16018-5 5 mg -

6 - 10 business days*

Cay16018-10 10 mg -

6 - 10 business days*

Cay16018-25 25 mg -

6 - 10 business days*

Cay16018-50 50 mg -

6 - 10 business days*

Camostat is a protease inhibitor. It inhibits trypsin (Ki = 1 nM), as well as various... more
Product information "Camostat (mesylate)"
Camostat is a protease inhibitor. It inhibits trypsin (Ki = 1 nM), as well as various inflammatory proteases, including plasmin, kallikrein, and thrombin. Camostat (50 µM) inhibits entry of vesicular stomatitis virus (VSV) particles pseudotyped with severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 spike glycoprotein in Calu-3 cells and primary human lung epithelial cells. It reduces the number of SARS-CoV-2 genomic equivalents, a marker of infection, in Calu-3 cells. Camostat inhibits sodium channel function in human airway epithelial cells (IC50 = 50 nM) and enhances mucociliary clearance in sheep. Dietary administration of camostat (1 mg/kg) inhibits the production of TNF-alpha and chemokine (C-C motif) ligand 2 (CCL2) by monocytes, as well as proliferation of pancreatic stellate cells in a rat model of pancreatic fibrosis. Formal Name: 4-[[4-[(aminoiminomethyl)amino]benzoyl]oxy]-benzeneacetic acid, 2-(dimethylamino)-2-oxoethyl ester, monomethanesulfonate. CAS Number: 59721-29-8. Synonyms: Foipan, FOY 305. Molecular Formula: C20H22N4O5 . CH3SO3H. Formula Weight: 494.5. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: 25 mg/ml, DMSO: 25 mg/ml. lambdamax: 264 nm. SMILES: O=C(C1=CC=C(NC(N)=N)C=C1)OC2=CC=C(CC(OCC(N(C)C)=O)=O)C=C2.CS(=O)(O)=O. InChi Code: InChI=1S/C20H22N4O5.CH4O3S/c1-24(2)17(25)12-28-18(26)11-13-3-9-16(10-4-13)29-19(27)14-5-7-15(8-6-14)23-20(21)22,1-5(2,3)4/h3-10H,11-12H2,1-2H3,(H4,21,22,23),1H3,(H,2,3,4). InChi Key: FSEKIHNIDBATFG-UHFFFAOYSA-N.
Keywords: Foipan, FOY 305, 4-[[4-[(aminoiminomethyl)amino]benzoyl]oxy]-benzeneacetic acid, 2-(dimethylamino)-2-oxoethyl ester, monomethanesulfonate
Supplier: Cayman Chemical
Supplier-Nr: 16018


Application: Serine protease inhibitor
MW: 494.5 D
Formula: C20H22N4O5 . CH3SO3H
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 59721-29-8| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319, H335, H400
P Phrases: P261, P264, P271, P273, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P391, P403+233, P405, P501
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow. more
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Camostat (mesylate)"
Write a review
or to review a product.