Butoconazole (nitrate)

Butoconazole is an imidazole antifungal agent that completely inhibits growth of a variety of fungi in vitro when used at concentrations of 0.05-30 µg/ml. It is active against vaginal infections of pure and mixed strains of C. albicans in mice when used vaginally at concentrations of 0.25-2% and 0.1-1%, respectively. Formulations containing butoconazole have been used in the treatment of vaginal yeast infections.Formal Name: 1-[4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole, mononitrate. CAS Number: 64872-77-1. Synonyms: (±)-Butoconazole, RS-35887. Molecular Formula: C19H17Cl3N2S . HNO3. Formula Weight: 474.8. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml, Ethanol: 0.1 mg/ml. lambdamax: 203, 271 nm. SMILES: ClC1=CC=CC(Cl)=C1SC(CN2C=NC=C2)CCC3=CC=C(Cl)C=C3.O=[N](O)=O. InChi Code: InChI=1S/C19H17Cl3N2S.HNO3/c20-15-7-4-14(5-8-15)6-9-16(12-24-11-10-23-13-24)25-19-17(21)2-1-3-18(19)22,2-1(3)4/h1-5,7-8,10-11,13,16H,6,9,12H2,(H,2,3,4). InChi Key: ZHPWRQIPPNZNML-UHFFFAOYSA-N.