Auxinole

Auxinole is an antagonist of the auxin receptor transport inhibitor response 1 (TIR1). It inhibits indole 3-acetic acid-induced root shoot growth in Arabidopsis seedlings when used at a concentration of 20 µM. Auxinole (5 or 10 µM) prevents indole 3-acetic acid-induced increases in root hair growth, root gravitropism, the number of lateral roots, and indole 3-acetic acid-induced decreases in primary root length in Arabidopsis seedlings. It reduces the number of programmed cell death-induced perforations in A. madagascariensis leaves when used at a concentration of 25 µM.Formal Name: alpha-[2-(2,4-dimethylphenyl)-2-oxoethyl]-1H-indole-3-acetic acid. CAS Number: 86445-22-9. Molecular Formula: C20H19NO3. Formula Weight: 321.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: Soluble, DMSO: Soluble. SMILES: O=C(C(CC(C1=CC=C(C)C=C1C)=O)C2=CNC3=C2C=CC=C3)O. InChi Code: InChI=1S/C20H19NO3/c1-12-7-8-14(13(2)9-12)19(22)10-16(20(23)24)17-11-21-18-6-4-3-5-15(17)18/h3-9,11,16,21H,10H2,1-2H3,(H,23,24). InChi Key: HGUYAIJBXSQXGV-UHFFFAOYSA-N.