AT9283

AT9283
Item number Size Datasheet Manual SDS Delivery time Quantity Price
SYN-1011-M001 1 mg -

3 - 9 business days*

106.00€
SYN-1011-M005 5 mg -

3 - 9 business days*

198.00€
SYN-1011-M010 10 mg -

3 - 9 business days*

329.00€
SYN-1011-M050 50 mg -

3 - 9 business days*

975.00€
SYN-1011-M100 100 mg -

3 - 9 business days*

-
 
Soluble in DMSO or ethanol. Aurora kinases play a key role in the regulation of mitosis and in... more
Product information "AT9283"
Soluble in DMSO or ethanol. Aurora kinases play a key role in the regulation of mitosis and in recent years have become attractive targets for the treatment of cancer. AT9283 is a powerful inhibitor of Aurora A and B kinases as well as several other important kinases including JAK2 and Abl (T315I). AT9283 has also been shown effective in mouise xenograft models and has been studied as a possible clinical candidate. Effective IC(50) doses for Aurora kinases are in the low 2-3nM range, and inhibition of a number of other kinases including JAK2 has been reported at 1-10nM. Target: Aurora , Kinase Group: Other , Substrate: Serine-Threonine
Keywords: AT-9283
Supplier: SYNkinase
Supplier-Nr: 1011

Properties

Application: Aurora inhibitor
MW: 381,4 D
Formula: C19H23N7O2
Purity: >95%
Format: Solid

Database Information

CAS : 896466-04-9| Matching products
KEGG ID : K11481 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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