Ardisiacrispin A

Ardisiacrispin A is a triterpene saponin that has been found in Myrsine australis and has diverse biological activities. It inhibits the cytopathic effects of poliovirus type I and herpes simplex virus 1 (HSV-1) in the filter paper disk assay when used at a concentration of 40 µg/disk and is active against various Candida species (MICs = 80-160 µg/ml). Ardisiacrispin A (10 and 13 µM) induces apoptosis in HepG2 cells. It induces contractions in rat uterus preparations when used at a concentration of 7.5 µM.Formal Name: (3beta,16alpha,20beta)-13,28-epoxy-3-[(O-beta-D-glucopyranosyl-(1->2)-O-[O-beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranosyl-(1->4)]-alpha-L-arabinopyranosyl)oxy]-16-hydroxy-oleanan-29-al. CAS Number: 23643-61-0. Synonyms: Deglucocyclamin, LTS-4, Saxifragifolin B. Molecular Formula: C52H84O22. Formula Weight: 1061.2. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Ethanol: soluble. SMILES: C[C@]12[C@]3(CC[C@@]4([H])[C@]2(CC[C@]5([H])[C@@]4(CC[C@@H](C5(C)C)O[C@H]6[C@@H]([C@H]([C@H](CO6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O[C@H]8[C@@H]([C@H]([C@@H](CO8)O)O)O)O)O[C@@H]9O[C@@H]([C@H]([C@@H]([C@H]9O)O)O)CO)C)C)[C@@]%10([H])[C@@]([C@@H](C1)O)(CC[C@@](C)(C%10)C=O)CO3. InChi Code: InChI=1S/C52H84O22/c1-46(2)27-7-11-49(5)28(8-12-52-29-15-47(3,21-55)13-14-51(29,22-68-52)30(57)16-50(49,52)6)48(27,4)10-9-31(46)72-44-40(74-43-39(65)36(62)33(59)24(17-53)69-43)35(61)26(20-67-44)71-45-41(37(63)34(60)25(18-54)70-45)73-42-38(64)32(58)23(56)19-66-42/h21,23-45,53-54,56-65H,7-20,22H2,1-6H3/t23-,24-,25-,26+,27+,28-,29-,30-,31+,32+,33-,34-,35+,36+,37+,38-,39-,40-,41-,42+,43+,44+,45+,47+,48+,49-,50+,51-,52+/m1/s1. InChi Key: JXTOWLUQSHIIDP-VKKSEJOZSA-N. Origin: Plant/Unspecified sp..