AN-7

alpha-Lipoic acid is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form. It is an essential cofactor for decarboxylation reactions of the citric acid cycle and acts as a general antioxidant. AN-7 is a more lipophilic analog of alpha-lipoic acid with enhanced potency and 1.5-fold increased maximal capacity to stimulate glucose transport into myocytes. This identifies the analogs of lipoic acid as potential new treatments for diabetes.Formal Name: N,N'-1,3-propanediylbis-1,2-dithiolane-3-pentanamide. CAS Number: 691410-93-2. Molecular Formula: C19H34N2O2S4. Formula Weight: 450.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 20 mg/ml, DMSO:PBS (pH 7.2)(1:4): 0.15 mg/ml, Ethanol: 2 mg/ml. SMILES: O=C(CCCCC1SSCC1)NCCCNC(=O)CCCCC1SSCC1. InChi Code: InChI=1S/C19H34N2O2S4/c22-18(8-3-1-6-16-10-14-24-26-16)20-12-5-13-21-19(23)9-4-2-7-17-11-15-25-27-17/h16-17H,1-15H2,(H,20,22)(H,21,23). InChi Key: QGUXZRFEKWOQQL-UHFFFAOYSA-N.