alpha-Boswellic Acid

alpha-Boswellic acid is a pentacyclic triterpene and an isomer of beta-boswellic acid (Cay-11693) originally isolated from B. serrata. It increases Survivin and Reelin expression, decreases production of reactive oxygen species (ROS) and levels of hyperphosphorylated Tau, and inhibits apoptosis induced by streptozotocin (Cay-13104) in primary fetal human astrocytes. alpha-Boswellic acid (200 mg/kg) increases gastric juice pH and production of gastric wall mucus and decreases leukocyte infiltration, submucosal edema, and the formation of hemorrhagic lesions in a rat model of ethanol-induced gastric injury.Formal Name: (4beta)-3alpha-hydroxy-olean-12-en-23-oic acid. CAS Number: 471-66-9. Molecular Formula: C30H48O3. Formula Weight: 456.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMSO: 25 mg/ml, DMSO:PBS (pH 7.2) (1:2): 0.30 mg/ml, Ethanol: 5 mg/ml. SMILES: O[C@@H]1CC[C@@]2(C)[C@](CC[C@]3(C)[C@]2([H])CC=C4[C@@]3(C)CC[C@]5(C)[C@@]4([H])CC(C)(C)CC5)([H])[C@]1(C(O)=O)C. InChi Code: InChI=1S/C30H48O3/c1-25(2)14-15-26(3)16-17-28(5)19(20(26)18-25)8-9-21-27(4)12-11-23(31)30(7,24(32)33)22(27)10-13-29(21,28)6/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21+,22+,23+,26+,27+,28+,29+,30?/m0/s1. InChi Key: BZXULBWGROURAF-LDWVVYRUSA-N. Origin: Plant/Boswellia carterii.