alpha-acetyl Boswellic Acid

alpha-acetyl Boswellic acid is a pentacyclic triterpene and isomer of beta-acetyl-boswellic acid (Cay-11674) originally isolated from B. serrata. It inhibits LPS-induced TNF-alpha mRNA expression in monocytes as well as NF-kappaB activity in HEK293 cells when used at a concentration of 10 µM. alpha-acetyl Boswellic acid also inhibits phosphorylation of IkappaBalpha mediated by IkappaB kinases (IKKs) in monocytes.Formal Name: (3alpha,4beta)-3-(acetyloxy)-olean-12-en-23-oic acid. CAS Number: 89913-60-0. Synonyms: ABA, 3-O-acetyl-alpha-Boswellic Acid, alpha-Boswellic Acid Acetate. Molecular Formula: C32H50O4. Formula Weight: 498.7. Purity: >99%. Formulation: (Request formulation change), A solid. Solubility: DMF: 25 mg/ml, DMSO: 25 mg/ml, Ethanol: 5 mg/ml. SMILES: CC1(C)CC[C@]2(C)CC[C@@]3(C)[C@@]4(C)[C@]([C@](CC[C@@H](OC(C)=O)[C@@]5(C(O)=O)C)(C)[C@@]5([H])CC4)([H])CC=C3[C@]2([H])C1. InChi Code: InChI=1S/C32H50O4/c1-20(33)36-25-12-13-29(5)23-10-9-21-22-19-27(2,3)15-16-28(22,4)17-18-30(21,6)31(23,7)14-11-24(29)32(25,8)26(34)35/h9,22-25H,10-19H2,1-8H3,(H,34,35)/t22-,23+,24+,25+,28+,29+,30+,31+,32?/m0/s1. InChi Key: IAWGZKRQDHPFCZ-KUZXTENQSA-N. Origin: Plant/Boswelli aserrata.