This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Free fatty acid receptor 4 (FFAR4/GPR120) is a G protein-coupled receptor expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long chain free fatty acids. omega-3 Fatty acids, such as docosahexaenoic acid (Cay-90310) and eicosapentaenoic acid (Cay-90110), initiate FFAR4 signaling, resulting in inhibition of toll-like receptor and TNF-alpha inflammatory signaling pathways in a beta-arrestin2/TAB1 dependent manner. AH 7614 is a selective FFAR4 antagonist (IC50s = 0.079 and 25 µM for human FFAR4 and FFAR1 receptors, respectively). In U2OS osteosarcoma cells expressing the FFAR4 receptor, it has been shown to inhibit intracellular calcium accumulation induced by either linoleic acid or an FFAR4 agonist.Formal Name: 4-methyl-N-9H-xanthen-9-yl-benzenesulfonamide. CAS Number: 6326-06-3. Synonyms: NSC 31171, N-xanthen-9-yl-p-Toluenesulfonamide. Molecular Formula: C20H17NO3S. Formula Weight: 351.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml. lambdamax: 290 nm. SMILES: CC1=CC=C(S(NC2C(C=CC=C3)=C3OC4=C2C=CC=C4)(=O)=O)C=C1. InChi Code: InChI=1S/C20H17NO3S/c1-14-10-12-15(13-11-14)25(22,23)21-20-16-6-2-4-8-18(16)24-19-9-5-3-7-17(19)20/h2-13,20-21H,1H3. InChi Key: OZCQEUZTOAAWDK-UHFFFAOYSA-N.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
More information