Acetyl-L-carnitine (chloride)

Acetyl-L-carnitine is an acetylated form of the essential mitochondrial metabolite L-carnitine (Cay-21489) that is catabolized by plasma esterases into carnitine. Acetyl-L-carnitine facilitates the uptake of acetyl-CoA into mitochondria during fatty acid oxidation, enhances acetylcholine production, and stimulates protein and membrane phospholipid synthesis. In vivo, acetyl-L-carnitine (100 mg/kg) increases mGlu2/3 receptor protein levels and mechanical pain thresholds in a mouse model of chronic inflammatory pain induced by complete Freund's adjuvant.Formal Name: 2R-(acetyloxy)-3-carboxy-N,N,N-trimethyl-1-propanaminium, monochloride. CAS Number: 5080-50-2. Synonyms: ALCAR, L-Acetylcarnitine, C2:0 Carnitine, CAR 2:0, L-Carnitine acetyl ester. Molecular Formula: C9H18NO4 . Cl. Formula Weight: 239.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 10 mg/ml, Ethanol: 20 mg/ml. lambdamax: 209 nm. SMILES: OC(C[C@@H](OC(C)=O)C[N+](C)(C)C)=O.[Cl-]. InChi Code: InChI=1S/C9H17NO4.ClH/c1-7(11)14-8(5-9(12)13)6-10(2,3)4,/h8H,5-6H2,1-4H3,1H/t8-,/m1./s1. InChi Key: JATPLOXBFFRHDN-DDWIOCJRSA-N.