7-Methylguanosine

7-Methylguanosine is a methylated form of the purine nucleoside guanosine (Cay-27702). It is an RNA modification that is present in the 5'-terminal cap of mRNA, where it promotes translation, as well as in tRNA, where it stabilizes the tRNA structure. 7-Methylguanosine has been used as a substrate to measure the activity of purine nucleoside phosphorylase (PNP). Urinary 7-methylguanosine levels are decreased in patients with prostate cancer.Formal Name: 7-methyl-guanosine. CAS Number: 20244-86-4. Synonyms: m7G. Molecular Formula: C11H15N5O5. Formula Weight: 297.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: 0.1 M HCl: 10 mg/ml, DMSO: 10 mg/ml. lambdamax: 261, 283 nm. SMILES: O=C1C2=C(N([C@H]3[C@H](O)[C@H](O)[C@@H](C[O-])O3)C=[N+]2C)N=C(N)N1. InChi Code: InChI=1S/C11H15N5O5/c1-15-3-16(8-5(15)9(20)14-11(12)13-8)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,18-19H,2H2,1H3,(H3,12,13,14,20)/t4-,6-,7-,10-/m1/s1. InChi Key: GBTRZXQMVWGLQX-KQYNXXCUSA-N.