7-Ethoxy-4-(trifluoromethyl)coumarin

7-Ethoxy-5-(trifluoromethyl)coumarin is a fluorogenic substrate for cytochrome P450s (CYPs). Upon O-deethylation by CYPs, 7-hydroxy-4-(trifluoromethyl)coumarin (HFC) is released and its fluorescence can be used to quantify CYP activity. HFC displays excitation/emission maxima of 410/510 nm, respectively.Formal Name: 7-ethoxy-4-(trifluoromethyl)-2H-1-benzopyran-2-one. CAS Number: 115453-82-2. Synonyms: EFC. Molecular Formula: C12H9F3O3. Formula Weight: 258.2. Purity: >95%. Emission: 510 nm. Excitation: 410 nm. Formulation: (Request formulation change), A solid. Solubility: Chloroform: slightly soluble, Methanol: slightly soluble. SMILES: O=C1OC2=C(C(C(F)(F)F)=C1)C=CC(OCC)=C2. InChi Code: InChI=1S/C12H9F3O3/c1-2-17-7-3-4-8-9(12(13,14)15)6-11(16)18-10(8)5-7/h3-6H,2H2,1H3. InChi Key: OLHOIERZAZMHGK-UHFFFAOYSA-N.