5-Octyl L-glutamate

While extracellular glutamic acid is an excitatory neurotransmitter, intracellular glutamic acid is an amino acid that serves numerous metabolic roles, including as a precursor for alpha-ketoglutarate. 5-Octyl L-glutamate, also known as 5-octyl ester glutamic acid, is a stable, cell-permeable molecule which generates free glutamic acid upon hydrolysis of the ester bond by cytoplasmic esterases. It may be used in experiments to increase levels of cytoplasmic glutamic acid. Alternatively, 5-octyl L-glutamate can be used to synthesize 5-octyl ester derivatives, including 5-octyl alpha-ketoglutarate, for delivery to cells.Formal Name: L-glutamic acid, 5-octyl ester. CAS Number: 4852-91-9. Synonyms: NSC 522645, 5-Octyl ester L-glutamic acid. Molecular Formula: C13H25NO4. Formula Weight: 259.4. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: Methanol: 1 mg/ml (heated). SMILES: CCCCCCCCOC(CC[C@H](N)C(O)=O)=O. InChi Code: InChI=1S/C13H25NO4/c1-2-3-4-5-6-7-10-18-12(15)9-8-11(14)13(16)17/h11H,2-10,14H2,1H3,(H,16,17). InChi Key: UCDDOKSXLQWTOD-UHFFFAOYSA-N.