5'-chloro-5'-Deoxyadenosine (hydrate)

5'-chloro-5'-Deoxyadenosine (hydrate) is a nucleoside analog used as a substrate in polyketide biosynthesis. S-(5'-adenosyl)-L-methionine (SAM, Cay-13956) can be converted to 5'-chloro-5'-deoxyadenosine in a reaction catalyzed by a SAM-dependent chlorinase. Through a 7-step route, 5'-chloro-5'-deoxyadenosine can be converted to chloroethylmalonyl-CoA, which has been shown to be involved in the biosynthesis of the anticancer agent salinosporamide A (Cay-10007311) in the marine bacterium S. tropica.Formal Name: 5'-chloro-5'-deoxy-adenosine, hydrate. CAS Number: 698999-09-6. Synonyms: 5'-ClDA, 5'-Deoxy-5'-chloroadenosine. Molecular Formula: C10H12ClN5O3 . XH2O. Formula Weight: 285.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml, DMSO: 25 mg/ml, Ethanol: 0.5 mg/ml. lambdamax: 258 nm. SMILES: O[C@H]1[C@@H](O)[C@H](N2C=NC3=C(N)N=CN=C32)O[C@@H]1CCl.O. InChi Code: InChI=1S/C10H12ClN5O3.H2O/c11-1-4-6(17)7(18)10(19-4)16-3-15-5-8(12)13-2-14-9(5)16,/h2-4,6-7,10,17-18H,1H2,(H2,12,13,14),1H2/t4-,6-,7-,10-,/m1./s1. InChi Key: XFACRIDKAAYORV-MCDZGGTQSA-N.