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4-Methoxycinnamic acid is a phenolic acid with diverse biological activities. It reduces A. fumigatus biofilm formation when used at concentrations ranging from 0.4 to 3.2 mM. In vivo, 4-methoxycinnamic acid (80 mg/kg) reduces the number of dysplastic aberrant crypt foci and dysplastic liver cells in a rat model of 1,2-dimethylhydrazine-induced colon carcinogenesis. It reverses MK-801-induced decreases in the preference ratio for the novel object in the novel object recognition test in mice. 4-Methoxycinnamic acid (40 mg/kg) reduces plasma glucose concentrations in a rat model of diabetes induced by streptozotocin (STZ, Cay-13104).Formal Name: 3-(4-methoxyphenyl)-2-propenoic acid. CAS Number: 830-09-1. Synonyms: NSC 5303, NSC 623437, O-methyl-p-Coumaric Acid, p-Methoxycinnamic Acid, para-Methoxycinnamic Acid. Molecular Formula: C10H10O3. Formula Weight: 178.2. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble. SMILES: O=C(C=CC1=CC=C(C=C1)OC)O. InChi Code: InChI=1S/C10H10O3/c1-13-9-5-2-8(3-6-9)4-7-10(11)12/h2-7H,1H3,(H,11,12). InChi Key: AFDXODALSZRGIH-UHFFFAOYSA-N. Origin: Synthetic.
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