4'-Aminomethyl-4,5',8-trimethylpsoralen

4'-Aminomethyl-4,5',8-trimethylpsoralen is a bifunctional photoreactive agent for crosslinking nucleic acids. In the dark, it intercalates into double-stranded regions in DNA or RNA. Upon long wavelength UV irradiation (e.g., 365 nm), 4'-aminomethyl-4,5',8-trimethylpsoralen first forms a covalent monoadduct with a pyrimidine base, followed by covalently linking with an adjacent pyrimidine on the opposite strand. Short wavelength UV irradiation (e.g., 254 nm) reverses this reaction. 4'-Aminomethyl-4,5',8-trimethylpsoralen has a high binding affinity for RNA and has been used to study different types of RNA from diverse organisms, including viruses.Formal Name: 3-(aminomethyl)-2,5,9-trimethyl-7H-furo[3,2-g][1]benzopyran-7-one. CAS Number: 64358-50-5. Synonyms: 4'-Aminomethyltrioxsalen. Molecular Formula: C15H15NO3. Formula Weight: 257.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml, Ethanol: 1 mg/ml. lambdamax: 240, 287 nm. SMILES: O=C1OC2=C(C)C3=C(C(CN)=C(C)O3)C=C2C(C)=C1. InChi Code: InChI=1S/C15H15NO3/c1-7-4-13(17)19-14-8(2)15-11(5-10(7)14)12(6-16)9(3)18-15/h4-5H,6,16H2,1-3H3. InChi Key: WBIICVGYYRRURR-UHFFFAOYSA-N.