4-Aminohippuric Acid

4-Aminohippuric acid is a substrate for various renal transporters that has been used in the study of anion uptake in the kidney. It is a substrate for organic anion transporter 1 (OAT1, Km = 14.3 µM in X. laevis oocytes), the human inorganic phosphate transporter (NPT1, Km = 2.66 mM in HEK293 cells), and apical multidrug resistance protein (MDR2, Km = 880 µM in HEK293 cells). 4-Aminohippuric acid is a glycine amide form of 4-aminobenzoic acid (Cay-18659). Formulations containing 4-aminohippuric acid have been used as markers to determine renal plasma flow.Formal Name: N-(4-aminobenzoyl)-glycine. CAS Number: 61-78-9. Synonyms: p-Aminohippuric Acid, para-Aminohippuric Acid, NSC 7550, NSC 13064. Molecular Formula: C9H10N2O3. Formula Weight: 194.2. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 33 mg/ml, DMF:PBS (pH7.2) (1:30): 0.03 mg/ml, DMSO: 20 mg/ml. lambdamax: 283 nm. SMILES: NC1=CC=C(C(NCC(O)=O)=O)C=C1. InChi Code: InChI=1S/C9H10N2O3/c10-7-3-1-6(2-4-7)9(14)11-5-8(12)13/h1-4H,5,10H2,(H,11,14)(H,12,13). InChi Key: HSMNQINEKMPTIC-UHFFFAOYSA-N.