27 products were found matching "K08203"!

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Probenecid
Probenecid

Item number: Cay14981-10

Probenecid is a benzoic acid derivative that inhibits organic anion transporters (OATs) and the ATP-binding cassette transporter (ABCC1) multidrug resistance protein 1 (MRP1) and activates the transient receptor potential (TRP) channel TRPV2. It inhibits OAT1, OAT3, and OAT6 (Kis = 6.3, 9.0, and 8.4 µM,...
Keywords: NSC 18786, 4-[(dipropylamino)sulfonyl]-benzoic acid
Application: Uricosuric, organic anion transporter inhibitor
CAS 57-66-9
MW: 285.4 D
From 43.00€ *
Review
Steviol
Steviol

Item number: Cay10011344-10

Steviol is the aglycon derivative of steviol glycosides, which are natural sweeteners isolated from S. rebaudiana. Steviol inhibits human organic anion transporters (hOATs) in uptake assays using murine cells from the S2 segment of proximal tubules. It is selective for hOAT1 and hOAT3 over hOAT2 and hOAT4 (IC50s =...
Keywords: Hydroxy Dehydrostevic Acid, NSC 226902, (4alpha)-13-hydroxy-kaur-16-en-18-oic acid
Application: OAT1 / OAT3 inhibitor
CAS 471-80-7
MW: 318.5 D
From 115.00€ *
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4-Aminohippuric Acid
4-Aminohippuric Acid

Item number: Cay23726-5

4-Aminohippuric acid is a substrate for various renal transporters that has been used in the study of anion uptake in the kidney. It is a substrate for organic anion transporter 1 (OAT1, Km = 14.3 µM in X. laevis oocytes), the human inorganic phosphate transporter (NPT1, Km = 2.66 mM in HEK293 cells), and apical...
Keywords: p-Aminohippuric Acid, para-Aminohippuric Acid, NSC 13064, NSC 7550, N-(4-aminobenzoyl)-glycine
Application: Renal transporter substrate
CAS 61-78-9
MW: 194.2 D
From 50.00€ *
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4-Hydroxyhippuric Acid
4-Hydroxyhippuric Acid

Item number: Cay30115-100

4-Hydroxyhippuric Acid is a dihydroxy phenolic acid inhibitor of organic anion transporter 1 (OAT1, IC50 = 25 µM in opossum kidney cells). It increases the production of free radicals in opossum kidney cells expressing human OAT1. 4-Hydroxyhippuric Acid reduces the secretion of TNF-alpha, but not IL-1beta or IL-6,...
Keywords: para-Hydroxyhippuric Acid, 4-Hydroxyhippuric Acid, N-(4-hydroxybenzoyl)-glycine
Application: OAT1 inhibitor
CAS 2482-25-9
MW: 195.2 D
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Anti-SLC22A6
Anti-SLC22A6

Item number: E-AB-16016.20

The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have...
Keywords: Anti-OAT1, Anti-hPAHT, Anti-hOAT1, Anti-hROAT1, Anti-SLC22A6, Anti-PAH transporter, Anti-Organic anion transporter 1,...
Application: WB, IHC, ELISA
Host: Rabbit
Species reactivity: human, rat
From 71.00€ *
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Anti-SLC22A6
Anti-SLC22A6

Item number: NSJ-R30768

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Solute carrier family 22 (organic anion transporter), member 6, also called OAT1 or PAHT, is a protein that in humans is encoded by the SLC22A6 gene, which is also a member of the organic anion transporter (OAT) family of proteins. It is a transmembrane protein...
Keywords: Anti-OAT1, Anti-hOAT1, Anti-hPAHT, Anti-hROAT1, Anti-SLC22A6, Anti-PAH transporter, Anti-Organic anion transporter 1,...
Application: WB, IHC (paraffin)
Host: Rabbit
Species reactivity: human, rat
755.00€ *
Review
Anti-SLC22A6
Anti-SLC22A6

Item number: E-AB-12825.120

The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have...
Keywords: Anti-OAT1, Anti-hPAHT, Anti-hOAT1, Anti-hROAT1, Anti-SLC22A6, Anti-PAH transporter, Anti-Organic anion transporter 1,...
Application: WB, IHC, ELISA
Host: Rabbit
Species reactivity: human, rat
From 71.00€ *
Review
Probenecid-d14
Probenecid-d14

Item number: Cay26787-5

Probenecid-d14 is intended for use as an internal standard for the quantification of probenecid (Cay-14981) by GC- or LC-MS. Probenecid is a benzoic acid derivative that inhibits organic anion transporters (OATs) but activates the transient receptor potential (TRP) channel TRPV2. It inhibits OAT1, OAT3, and OAT6...
Keywords: 4-[[di(propyl-1,1,2,2,3,3,3-d7)amino]sulfonyl]-benzoic acid
Application: GC-MS, LC-MS, Quantification, Internal standard, Uricosuric, Organic anion transporter inhibitor
CAS 1189657-87-1
MW: 299.4 D
From 195.00€ *
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Rebaudioside D
Rebaudioside D

Item number: Cay27880-10

Rebaudioside D is a natural non-caloric sweetener. It is a steviol glycoside that has been found in S. rebaudiana leaves. Rebaudioside D, similarly to rebaudioside A (Cay-11894) and rebaudioside C (Cay-11895), is metabolized by gut microbiota to steviol (Cay-10011344), a compound whose safety is widely...
Keywords: (4alpha)-13-[(O-beta-D-glucopyranosyl-(1->2)-O-[beta-D-glucopyranosyl-(1->3)]-beta-D-glucopyranosyl)oxy]-kaur-16-en-18-oic...
Application: Natural non-caloric sweetener
CAS 63279-13-0
MW: 1129.2 D
From 82.00€ *
Review
Anti-SLC22A6 / OAT1
Anti-SLC22A6 / OAT1

Item number: ARG41225.50

Protein function: Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the...
Keywords: Anti-OAT1, Anti-hPAHT, Anti-hOAT1, Anti-hROAT1, Anti-SLC22A6, Anti-PAH transporter, Anti-Organic anion transporter 1,...
Application: IHC (paraffin), WB
Host: Rabbit
Species reactivity: human, rat
520.00€ *
Review
Anti-SLC22A6 / OAT1
Anti-SLC22A6 / OAT1

Item number: ARG66609.100

Protein function: Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the...
Keywords: Anti-OAT1, Anti-hPAHT, Anti-hOAT1, Anti-hROAT1, Anti-SLC22A6, Anti-PAH transporter, Anti-Organic anion transporter 1,...
Application: IHC (paraffin), WB
Host: Rabbit
Species reactivity: human, mouse
584.00€ *
Review
Anti-SLC22A6
Anti-SLC22A6

Item number: G-CAB3184.100

Application: WB
Host: Rabbit
Species reactivity: human, mouse
From 352.00€ *
Review
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