3-chloro-L-Tyrosine

3-chloro-L-Tyrosine is a derivative of L-tyrosine. It is formed from a reaction between the myeloperoxidase (MPO) product hypochlorous acid and L-tyrosine and has been used as a biomarker of oxidative damage induced by MPO. Plasma and atherosclerotic plaque levels of 3-chloro-L-tyrosine are increased in patients with various cardiovascular diseases. Plasma levels of 3-chloro-L-tyrosine are also increased in patients with colorectal cancer. 3-chloro-L-Tyrosine is also formed in blood upon chlorine gas exposure and has been used as an indicator of chlorine poisoning during autopsy.CAS Number: 7423-93-0. Synonyms: 3-Chlorotyrosine, 3-CT. Molecular Formula: C9H10ClNO3. Formula Weight: 215.6. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Slightly soluble, Ethanol: Slightly soluble, PBS (pH 7.2): 1 mg/mL. SMILES: OC([C@@H](N)CC1=CC(Cl)=C(C=C1)O)=O. InChi Code: InChI=1S/C9H10ClNO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1. InChi Key: ACWBBAGYTKWBCD-ZETCQYMHSA-N.