3,4'-5-Trihydroxystilbene-3-beta-D-Glucopyranoside

3,4'-5-Trihydroxystilbene-3-beta-D-glucopyranoside is a stilbene glucoside that has been found in V. vinifera and has diverse biological activities. It reduces the growth of SKOV3 ovarian cancer cell 3D aggregates in a concentration-dependent manner. 3,4'-5-Trihydroxystilbene-3-beta-D-glucopyranoside (10 and 20 µg/ml) inhibits IL-17 production in activated peripheral blood mononuclear cells (PBMCs). It inhibits the loss of glutathione peroxidase 4 (GPX4) activity induced by the ferroptosis inducer hemin in Neuro2a neuroblastoma cells. 3,4'-5-Trihydroxystilbene-3-beta-D-glucopyranoside (50 mg/kg) reduces escape latency in a rat model of vascular dementia induced by four-vessel occlusion (4-VO).Formal Name: 3-hydroxy-5-[2-(4-hydroxyphenyl)ethenyl]phenyl beta-D-glucopyranoside. CAS Number: 65914-17-2. Synonyms: (E/Z)-Polydatin, Reservatrol 3-beta-mono-D-Glucoside, Resveratrol 3-O-beta-D-Glucopyranoside, Trihydroxystilbene-3-beta-D-Glucopyranoside. Molecular Formula: C20H22O8. Formula Weight: 390.4. Purity: >98% (mixture of isomers). Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 50 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 0.25 mg/ml. lambdamax: 217, 307, 320 nm. SMILES: O[C@H]([C@@H](O)[C@@H]1O)[C@@H](O[C@@H]1CO)OC2=CC(C=CC3=CC=C(O)C=C3)=CC(O)=C2. InChi Code: InChI=1S/C20H22O8/c21-10-16-17(24)18(25)19(26)20(28-16)27-15-8-12(7-14(23)9-15)2-1-11-3-5-13(22)6-4-11/h1-9,16-26H,10H2/t16-,17-,18+,19-,20-/m1/s1. InChi Key: HSTZMXCBWJGKHG-OUUBHVDSSA-N.