2-Phenyl-2-(1-piperidinyl)propane

2-Phenyl-2-(1-piperidinyl)propane is an analog of phencyclidine that acts as a mechanism-based inactivator of human cytochrome P450 (CYP) 2B6 (Ki = 5.6 µM, IC50 = 5.1 µM). It is 15-fold more selective for inhibition of CYP2B6 over CYP2D6 and 40-60-fold more selective for CYP2B6 over CYP1A2, CYP2A6, CYP2Cs, and CYP3A.Formal Name: 1-(1-methyl-1-phenylethyl)-piperidine. CAS Number: 92321-29-4. Synonyms: 1-(alpha,alpha-dimethylbenzyl)-Piperidine, PPP. Molecular Formula: C14H21N. Formula Weight: 203.3. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml. SMILES: CC(C1=CC=CC=C1)(C)N2CCCCC2. InChi Code: InChI=1S/C14H21N/c1-14(2,13-9-5-3-6-10-13)15-11-7-4-8-12-15/h3,5-6,9-10H,4,7-8,11-12H2,1-2H3. InChi Key: HORGQLWAZQOQNU-UHFFFAOYSA-N.