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Product information "2-Aminopurine (hydrochloride)"
2-Aminopurine is a fluorescent analog of guanosine and adenosine that is used as a site-specific probe of nucleic acid structure and dynamics. It base pairs with cytosine in a wobble configuration or with thymine in a Watson-Crick geometry. In addition to its usefulness in studies of base stacking interactions, 2-aminopurine has been used as a probe for DNA base flipping by methyl transferases. 2-Aminopurine exhibits an excitation/emission of 320/381 nm, respectively, when adjusted to reduce interference with DNA base absorption as well as tryptophan fluorescence. 2-Aminopurine inhibits the double-stranded RNA-dependent protein kinase, protein kinase R, whose activity mediates antiviral defense and participates in toll-like receptor signaling.Formal Name: 9H-purin-2-amine, dihydrochloride. CAS Number: 1428126-74-2. Synonyms: 2-AP. Molecular Formula: C5H5N5 . 2HCl. Formula Weight: 208.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 5 mg/ml. lambdamax: 216, 305 nm. SMILES: NC1=NC2=NC=NC2=CN1.Cl.Cl. InChi Code: InChI=1S/C5H5N5.2ClH/c6-5-7-1-3-4(10-5)9-2-8-3,,/h1-2H,(H3,6,7,8,9,10),2*1H. InChi Key: ZMYNIVFDDGHSJU-UHFFFAOYSA-N.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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