2-Amino-5-fluorobenzoic Acid

2-Amino-5-fluorobenzoic acid is a toxic antimetabolite for the tryptophan pathway in yeast that can be used to counterselect for TRP1, a commonly used genetic marker in S. cerevisiae. Because this trp1 strain lacks the enzymes required for the conversion of anthranilic acid to tryptophan, it is resistant to 2-amino-5-fluorobenzoic acid feedback inhibition, enabling a growth-based, positive selection of the TRP1 marker. 2-Amino-5-fluorobenzoic acid is frequently used in genetic procedures that involve plasmid manipulations.Formal Name: 2-amino-5-fluoro-benzoic acid. CAS Number: 446-08-2. Synonyms: 5-FAA, 5-Fluoroanthranilic Acid, NSC 513308. Molecular Formula: C7H6FNO2. Formula Weight: 155.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 20 mg/ml, PBS (pH 7.2): 0.25 mg/ml. lambdamax: 215, 245, 348 nm. SMILES: NC1=C(C(O)=O)C=C(F)C=C1. InChi Code: InChI=1S/C7H6FNO2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,9H2,(H,10,11). InChi Key: FPQMGQZTBWIHDN-UHFFFAOYSA-N.