10,11-dihydro-10-hydroxy Carbamazepine

10,11-dihydro-10-hydroxy Carbamazepine is an antiepileptic agent and active metabolite of the prodrug oxcarbazepine (Cay-17340). It is a racemic mixture of (R)- and (S)-10,11-dihydro-10-hydroxy carbamazepine. (S)-10,11-dihydro-10-hydroxy Carbamazepine protects against seizures induced by maximal electroshock (MES) in rats by 42% while (R)-10,11-dihydro-10-hydroxy carbamazepine only protects against MES-induced seizures by 22.5%.Formal Name: 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide. CAS Number: 29331-92-8. Synonyms: BIA 2-005, 10,11-dihydro-10-hydroxy CBZ, 10,11-hydroxy-10,11 Dihydrocarbamezer, GP 47779, Licarbazepine. Molecular Formula: C15H14N2O2. Formula Weight: 254.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMSO: 25 mg/ml, DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml, Ethanol: 3 mg/ml. SMILES: NC(N1C2=C(C=CC=C2)CC(O)C3=C1C=CC=C3)=O. InChi Code: InChI=1S/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19). InChi Key: BMPDWHIDQYTSHX-UHFFFAOYSA-N.