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1,4-Dicaffeoylquinic acid is a polyphenol that has been found in C. coronarium and has diverse biological activities. It scavenges DPPH (Cay-14805) radicals and inhibits xanthine oxidase (XO, IC50 = 7.36 µM). 1,4-Dicaffeoylquinic acid (25 µM) decreases protein levels of tyrosinase and microphthalmia-associated transcription factor (MITF) in B16/F1 murine melanocytes, inhibits melanogenesis in the same cells, and decreases tyrosinase activity in B16/F1 cell lysates. It increases biliary flow in rats in a dose-dependent manner.Formal Name: (1alpha,3R,4alpha,5R)-rel-1,4-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3,5-dihydroxy-cyclohexanecarboxylic acid. CAS Number: 1182-34-9. Synonyms: 1,4-DCQA, 1,4-Dicaffeylquinic Acid. Molecular Formula: C25H24O12. Formula Weight: 516.5. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble. lambdamax: 220, 246, 330 nm. SMILES: OC(C=C1C=CC(O[C@]2(C[C@H]([C@H]([C@@H](C2)O)OC(C=CC3=CC(O)=C(C=C3)O)=O)O)C(O)=O)=O)=C(C=C1)O. InChi Code: InChI=1S/C25H24O12/c26-15-5-1-13(9-17(15)28)3-7-21(32)36-23-19(30)11-25(24(34)35,12-20(23)31)37-22(33)8-4-14-2-6-16(27)18(29)10-14/h1-10,19-20,23,26-31H,11-12H2,(H,34,35)/t19-,20-,23-,25+/m1/s1. InChi Key: IYXQRCXQQWUFQV-BBLPPJRLSA-N. Origin: Plant/Lonicera japonica Thunb..
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