Maduramicin (ammonium salt)

Maduramicin (ammonium salt)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay34270-50 50 mg -

6 - 10 business days*

57.00€
Cay34270-100 100 mg -

6 - 10 business days*

97.00€
Cay34270-250 250 mg -

6 - 10 business days*

225.00€
Cay34270-500 500 mg -

6 - 10 business days*

423.00€
 
Maduramicin is a polyether ionophore antibiotic that has been found in Nocardia. It selectively... more
Product information "Maduramicin (ammonium salt)"
Maduramicin is a polyether ionophore antibiotic that has been found in Nocardia. It selectively binds to potassium, rubidium, sodium, lithium, and cesium ions over divalent cations. Maduramicin is active against Gram-positive bacteria (MICs = 0.9-125 µg/ml) but not Gram-negative bacteria (MICs = >1,000 µg/ml) or fungi (MICs = 250->1,000 µg/ml). It reduces the viability of asexual and gametocyte P. falciparum parasites (EC50s = 1.3 and 14.8 nM, respectively) and reduces P. berghei transmission in a mouse model of malaria when administered at doses of 4 and 8 mg/kg. Maduramicin (5-10 ppm in the diet) reduces the severity of lesions and completely protects chicks against mortality in a model of coccidiosis induced by E. tenella. Formulations containing maduramicin have been used in the treatment of coccidiosis in chickens.Formal Name: maduramicin alpha, monoammonium salt. CAS Number: 84878-61-5. Synonyms: Antibiotic X-14868A, CL 259,971, Maduramycin, Prinicin. Molecular Formula: C47H79O17 . NH4. Formula Weight: 934.2. Purity: >95%. Formulation: A solid. Solubility: DMF: 1 mg/ml. SMILES: [H][C@](O1)([C@@]2([H])O[C@@](O)(C)[C@H](C)C[C@@H]2C)C[C@H](O[C@@H]3C[C@H](OC)[C@@H](OC)[C@H](C)O3)[C@]1([H])[C@@](CC4)(C)O[C@@]4([H])[C@@](CC5)(C)O[C@@]65O[C@@]([C@@H](C)[C@]7([H])O[C@@](CC([O-])=O)(O)[C@@H](C)[C@H](OC)[C@H]7OC)([H])[C@H](C)[C@@H](O)C6.[NH4+]. InChi Code: InChI=1S/C47H80O17.H3N/c1-23-18-24(2)45(9,51)61-36(23)31-19-32(58-35-20-30(53-10)40(55-12)28(6)57-35)42(59-31)44(8)15-14-33(60-44)43(7)16-17-46(64-43)21-29(48)25(3)37(62-46)26(4)38-41(56-13)39(54-11)27(5)47(52,63-38)22-34(49)50,/h23-33,35-42,48,51-52H,14-22H2,1-13H3,(H,49,50),1H3/t23-,24+,25+,26+,27-,28-,29-,30-,31+,32-,33+,35+,36-,37-,38-,39-,40-,41-,42+,43-,44-,45-,46+,47+,/m0./s1. InChi Key: WQGJEAMPBSZCIF-HKSLRPGUSA-N. Origin: Synthetic.
Keywords: Antibiotic X-14868A, CL 259,971, Maduramycin, Prinicin, maduramicin alpha, monoammonium salt
Supplier: Cayman Chemical
Supplier-Nr: 34270

Properties

Application: Polyether ionophore antibiotic, Coccidiostat
MW: 934.2 D
Formula: C47H79O17 . NH4
Purity: >95%
Format: Solid

Database Information

CAS : 84878-61-5| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H300, H310, H319, H402
P Phrases: P262, P264, P270, P273, P280, P301+310, P302+352, P305+351+338, P310, P321, P330, P337+313, P361+364, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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