Ionomycin

Ionomycin
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10004974-1 1 mg -

6 - 10 business days*

44.00€
Cay10004974-5 5 mg -

6 - 10 business days*

208.00€
Cay10004974-10 10 mg -

6 - 10 business days*

394.00€
Cay10004974-25 25 mg -

6 - 10 business days*

767.00€
 
Ionomycin is a calcium ionophore originally isolated from S. conglobatus. It induces... more
Product information "Ionomycin"
Ionomycin is a calcium ionophore originally isolated from S. conglobatus. It induces intracellular calcium mobilization in X. laevis oocytes when used at a concentration of 5 µM. Ionomycin (5 µM) induces the formation of neutrophil extracellular traps (NETs) in isolated human neutrophils. Ionomycin in combination with phorbol 12-myristate 13-acetate (PMA, Cay-10008014) has commonly been used to induce the proliferation and activation of T cells, as well as to stimulate cytokine production in macrophages, in vitro. Formal Name: (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid. CAS Number: 56092-81-0. Molecular Formula: C41H72O9. Formula Weight: 709.0. Purity: >95%. Formulation: A solution in ethanol. Solubility: DMF: 2.5 mg/ml, DMSO: 1.4 mg/ml, Ethanol: 20 mg/ml, Ethanol:PBS (pH 7.2) (1:10): 0.1 mg/ml. lambdamax: 277 nm. SMILES: C[C@@H](O)[C@](O1)(C)CC[C@]1([H])[C@]2(C)CCC(C[C@H](O)[C@H](C)[C@H](O)[C@H](C)/C=C/C[C@@H](C)C[C@@H](C)/C(O)=C/C([C@@H](C)C[C@@H](C)C[C@H](C)CCC(O)=O)=O)O2. InChi Code: InChI=1S/C41H72O9/c1-25(21-29(5)34(43)24-35(44)30(6)22-27(3)20-26(2)14-15-38(46)47)12-11-13-28(4)39(48)31(7)36(45)23-33-16-18-41(10,49-33)37-17-19-40(9,50-37)32(8)42/h11,13,24-33,36-37,39,42-43,45,48H,12,14-23H2,1-10H3,(H,46,47)/b13-11+,34-24-/t25-,2. InChi Key: PGHMRUGBZOYCAA-KCZOVTJBSA-N. Origin: Bacteria/Streptomyces conglobatus.
Keywords: (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid
Supplier: Cayman Chemical
Supplier-Nr: 10004974

Properties

Application: Ca Ionophore
MW: 709 D
Formula: C41H72O9
Purity: >95%
Format: Solution

Database Information

CAS : 56092-81-0| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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