Clindamycin Phosphate

Clindamycin phosphate is a lincosamide antibiotic. It is active against P. acnes in vitro (MIC = 0.02 µg/ml). Topical administration of clindamycin phosphate (1% w/w) reduces the number of bacteria at the burn site in a mouse model of P. acnes burn infection. Formulations containing clindamycin phosphate have been used in the treatment of acne.Formal Name: methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-alpha-D-galacto-octopyranoside, 2-(dihydrogen phosphate). CAS Number: 24729-96-2. Synonyms: Clindamycin 2-Phosphate, DARE-BV1, NSC 618653, U-28508. Molecular Formula: C18H34ClN2O8PS. Formula Weight: 505.0. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: insol, DMSO: 2 mg/ml, Ethanol: insol, PBS (pH 7.2): 10 mg/ml. SMILES: O=C([C@@H]1C[C@H](CN1C)CCC)N[C@@H]([C@@]2([H])O[C@@H]([C@@H]([C@H]([C@H]2O)O)OP(O)(O)=O)SC)[C@@H](Cl)C. InChi Code: InChI=1S/C18H34ClN2O8PS/c1-5-6-10-7-11(21(3)8-10)17(24)20-12(9(2)19)15-13(22)14(23)16(18(28-15)31-4)29-30(25,26)27/h9-16,18,22-23H,5-8H2,1-4H3,(H,20,24)(H2,25,26,27)/t9-,10+,11-,12+,13+,14-,15+,16+,18+/m0/s1. InChi Key: UFUVLHLTWXBHGZ-MGZQPHGTSA-N.