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Isolated from Actinoplanes sp. Beige powder. Soluble in ethanol, DMSO or aqueous acetonitrile. Tetracyclic class II lantibiotic. Structurally related to mersacidine. Antibiotic. Antibacterial against Gram-positive bacteria and Gram-negative microorganisms. Specifically inhibits peptidoglycan synthesis in the cell wall of Gram-positive bacteria, resulting in the accumulation of both uridine 5'-disphosphate-N-acetylmuramylpentapeptide and lipid II. Has the ability to form a complex with lipid intermediate II (lipid II).
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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