Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used... read more »
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Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

63 from 64 pages
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Sandramycin
Sandramycin

Item number: S0091-01.1

Sandramycin is a high molecular weight, symmetric, cyclic depsipeptide belonging to the quinomycin class produced by Kribbella sp.. Sandramycin has potent antitumor and antibacterial activity and is thought to act by bis-intercalation of DNA. Source: Kribbella sp. MST-AS5567 , Apperance: White solid, , Solubility:...
CAS 100940-65-6
MW: 1221,3 D
560.00€ *
Review
Siomycin A (Mutabilycin, Sporangiomycin, Antibiotic 6741
Siomycin A (Mutabilycin, Sporangiomycin, Antibiotic 6741

Item number: S1013-86W.500

Siomycin is a macrocyclic antibiotic with potent and selective antibacterial activity discovered in 1969. Recently, siomycin was discovered to be a potent inhibitor of the oncogenic transcription factor-forkhead box M1, FoxM1 (previously known as HFH-11B, Trident, WIN or MPP2). The reduced transcription activity was...
CAS 12656-09-6
MW: 1648.87 D
623.00€ *
Review
Sterigmatocystin
Sterigmatocystin

Item number: S7973-49.1

Sterigmatocystin is a xanthone isolated by a number of groups in the 1950s as a mycotoxin produced by several species of Aspergillus associated with food and grain contamination. Sterigmatocystin is structurally related to the aflatoxins and while it is considered to be mutagenic, teratogenic and carcinogenic, it is...
CAS 10048-13-2
MW: 324,3 D
393.00€ *
Review
Streptonigrin (Bruneomycin, Nigrin, Rufocromomycin, Valacidin, Antibiotic RP 5278)
Streptonigrin (Bruneomycin, Nigrin, Rufocromomycin,...

Item number: S7975-09.1

Streptonigrin is an unusual aminoquinone with broad biological activity against bacteria, fungi, nematodes, viruses and tumor cells. Streptonigrin acts as a bioreductive agent, highly dependent on interactions with metal ions, notably iron, and plays an important role in free radical production through redox cycling...
CAS 3930-19-6
MW: 506,5 D
From 439.00€ *
Review
Terphenyllin
Terphenyllin

Item number: T2770.1

Terphenyllin is the dominant analogue of a family of polyphenyl fungal metabolites produced by Aspergillus candidus. The occurence of this metabolite is used as a criterion in the polyphasic taxonomy of A. candidus. Terphenyllin has not been extensively studied but has been reported to exhibit anti-oxidative...
CAS 52452-60-5
MW: 338,4 D
485.00€ *
Review
Thiostrepton (Bryamycin, Thiactin, Alaninamide, Antibiot
Thiostrepton (Bryamycin, Thiactin, Alaninamide, Antibiot

Item number: T3792-12.5

Thiostrepton is a macrocyclic antibiotic incorporating thiazoles and other atypical amino acids. Patented in 1961, thiostrepton has been used as an antibiotic and acts by binding to ribosomes to prevent the binding of the EF-G elongation factor and GTP to the 50S riobsomal subunit. Thiostrepton is an inducer of...
CAS 1393-48-2
MW: 1664.90 D
456.00€ *
Review
Verruculogen
Verruculogen

Item number: V2121-71.1

Verruculogen is a tremorgenic mycotoxin first isolated from Penicillium verruculosum in 1972 and the structure resolved as an indole alkaloid in 1974. Subsequent investigations have shown that verruculogen is produced by several species of Penicillium and Aspergillus and its presence is a useful taxonomic phenotypic...
CAS 12771-72-1
MW: 511,6 D
393.00€ *
Review
Virginiamycin S1 (Staphylomycin S, PA 114B2, Antibiotic
Virginiamycin S1 (Staphylomycin S, PA 114B2, Antibiotic

Item number: V2122-81.5

Virginiamycin S1 is one of a family of depsipeptide antibiotic co-produced with ostreogrycin A and used as a synergistic mixture. Virginiamycin S1 also known as Staphylomycin S and Factor S, among other synonyms were discovered independently and named by several groups leading to considerable confusion in the...
CAS 23152-29-6
MW: 823.90 D
560.00€ *
Review
Neomycin Sulfate (Streptomyces fradiae waksman)
Neomycin Sulfate (Streptomyces fradiae waksman)

Item number: N2010.1

Aminoglycoside antibiotic that inhibits translation by binding to the small subunit of prokaryotic ribosomes. Inhibitor of phospholipase C due to binding to inositol phospholipids. Neomycin inhibits phosphatidylcholine-phospholipase D activity. Blocks voltage sensitive Ca2+ channels without affecting Na+/Ca2+...
CAS 1405-10-3
MW: 908.90 D
From 78.00€ *
Review
Polymyxin B sulfate
Polymyxin B sulfate

Item number: LKT-P5747.1

Mixture of polymyxin B1, B2, B3 and B1-1 sulfates
Application: Antibacterial agent
CAS 1405-20-5
From 94.00€ *
Review
Tobramycin, Free Base
Tobramycin, Free Base

Item number: LKT-T5604.100

Aminoglycoside, protein translation inhibitor.
Keywords: Nebramycin factor 6, NF 6, Tobracin, Tobralex, Tobramaxin, Tobrex, O-3-Amino-3-deoxy-alpha-d-glucopyranosyl-(1->6)-O-...
Application: Protein synthesis inhibitor
CAS 32986-56-4
MW: 467,51 D
From 91.00€ *
Review
Oxolinic Acid
Oxolinic Acid

Item number: LKT-O9458.1

A quinolone antibiotic agent that inhibits the enzyme DNA gyrase. Also may act as a dopamine reuptake inhibitor.
Application: DNA gyrase inhibitor
CAS 14698-29-4
MW: 261.23 D
77.00€ *
Review
63 from 64 pages