WM3618F Viable Cells

Cells are sterile, validated by short tandem repeat profiling, and are tested as negative for mycoplasma. It is recommended that cell lines are tested for mycoplasma contamination and short tandem repeat (STR) profiling every 10 passages or each time a frozen seed stock is made. See cell culture protocol for additional details. WM3618F is a human metastatic uveal melanoma cell line displaying melanocytic morphology. These cells require 10% FBS to adhere to culture flask. This cell line was established from a lymph node metastases arising from uveal melanoma of a patient. Uveal melanoma is a rare type of cancer of an eye and can arise in the anterior (iris) or the posterior (ciliary body or choroid) uveal tract. Most uveal tract melanomas originate in the choroid. The ciliary body is less commonly a site of origin, and the iris is the least common. WM3618F cells match with WM3772F. These cells produce xenograft tumors when injected into immunocompromised mice.