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NFAT Luciferase Reporter CHO Cell Line (PKC/Ca2+...
Item number: BPS-78569
The NFAT Luciferase Reporter CHO cell line (PKC/Ca2+ Signaling Pathway) contains a firefly luciferase gene under the control of NFAT response element stably integrated into CHO K1 cells. This cell line is validated for its response to phorbol 12-myristate 13-acetate (PMA) in the presence of ionomycin.
| Keywords: | TonEBP, NF-AT5, TonE-binding protein, T-cell transcription factor NFAT5, Nuclear factor of activated T-cells 5,... |
| Application: | NFAT stimulation monitoring, PKC/ Ca2+ activator/inhibitor screening |
| Species reactivity: | human |
3,056.00€
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B7-H4 CHO Cell Line (low Expression)
Item number: BPS-78586-L
B7-H4 CHO Cell line is a recombinant clonal stable CHO-K1 cell line constitutively expressing full length human B7- H4 protein, also known as V-set domain-containing T-cell activation inhibitor 1 (VTCN1), (NM_024626.4). Surface expression of B7-H4 was confirmed by flow cytometry. Each stable clonal cell line was...
| Keywords: | B7-H4, B7h.5, Protein B7S1, B7 homolog 4, T-cell costimulatory molecule B7x, Immune costimulatory protein B7-H4, V-set... |
| Application: | Antibody screening/validation, drug discovery, modulator/inhibitor screening (cellular context) |
| Species reactivity: | human |
9,308.00€
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StemBright(TM) Luciferase iPS Cell Pool
Item number: BPS-78594
The StemBright(TM) Luciferase iPS Cell Pool constitutively expresses the firefly luciferase gene under the control of a CMV promoter, introduced via lentiviral transduction (Firefly Luciferase Lentivirus, BPS Bioscience #79692). Luciferase activity can be used to monitor cell viability, both in vitro and in vivo.
| Keywords: | Luciferase, Luciferin 4-monooxygenase, |
| Application: | Cell viability assays, co-culture assays, in vivo localization monitoring, bioluminescent imaging (BLI) |
11,077.00€
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Claudin-9 CHO Cell Line
Item number: BPS-78687
Recombinant clonal CHO cell line stably expressing full-length human claudin-9 (CLDN9 gene accession number NM_020982). Surface expression of claudin-9 was confirmed by flow cytometry. The stable clonal cell line was selected for high levels of claudin-9 expression compared to the parental CHO-K1 cell line.
| Keywords: | CLDN9, Claudin-9, |
| Application: | Antibody screening/validation, drug discovery, inhibitor screening (cellular context), binding assays |
| Species reactivity: | human |
9,709.00€
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MUC16 (CA125), variant 4 (region 13785-14507) CHO Cell Line
Item number: BPS-78848
Engineered CHO cell line stably expressing human C-terminus MUC16 (CA125) transcript variant 4, from amino acid 13785 to 14507 (NM_024690.2). This portion of MUC16 contains several of the extracellular SEA modules, the transmembrane domain, and the short cytoplasmic tail of the protein. Surface expression of MUC16...
| Keywords: | MUC-16, CA-125, Mucin-16, Ovarian carcinoma antigen CA125, Ovarian cancer-related tumor marker CA125, |
| Application: | Screening, antibody validation, drug discovery, binding assays |
| Species reactivity: | human |
9,308.00€
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Normal Human Peripheral Blood Mononuclear Cells, Frozen
Item number: BPS-79059-1
Cryopreserved vial (30 x 10^6 cells or 100 x 10^6 cells, resp.) of freshly isolated primary human peripheral blood mononuclear cells (PBMCs) from a healthy donor, isolated from leukapheresis / apheresis samples using Ficoll gradient. After isolation, the PBMCs were stained to identify sub populations and evaluated...
| Keywords: | PBMC, primary cells, |
| Application: | Immunotherapy studies |
From 326.00€
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BirA-transformed Competent E. coli cells
Item number: BPS-27462
BirA-transformed Competent E. coli cells are supplied as 10 x 100 µl vials. Strain BL21, a chemically competent E. coli B strain, contains an IPTG-inducible BirA expression plasmid and constitutively-expressed streptomycin/spectinomycin resistance gene. These cells are compatible with most cloning vectors and are...
| Keywords: | bioR, b3973, Biotin--protein ligase, Biotin operon repressor, Bifunctional ligase/repressor BirA,... |
| Application: | Biotin labelling of recombinant proteins |
723.00€
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NF-kappaB Luciferase Reporter Jurkat Cell Line
Item number: BPS-60651
NF-kappaB luciferase reporter construct is stably integrated into the genome of Jurkat T- cells. The firefly luciferase gene is controlled by 4 copies of NF-kB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-kappaB transcription factors bind to the DNA...
| Keywords: | NF-kappaB cell line, NFkappaB cell line, luciferase reporter, NF-kB cell line, NFkB cell line, |
| Application: | NF-kappaB signaling monitoring |
3,329.00€
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RARalpha Reporter Cell Line (2x10(6) cells)
Item number: BPS-60503
2x10(6) cells. The RARalpha Reporter (Luc)-HEK293 Cell Line is designed for monitoring the activity of retinoic acid receptor alpha (RARalpha). The RARalpha Reporter (Luc)-HEK293 Cell Line contains a firefly luciferase gene under the control of retinoic acid response elements stably integrated into HEK293 cells...
| Keywords: | RARA, NR1B1, RAR-alpha, Retinoic acid receptor alpha, Nuclear receptor subfamily 1 group B member 1, |
| Application: | RARalpha reporter assays |
| Host: | Human cells |
| Species reactivity: | human |
3,193.00€
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NFAT Reporter (Luc) - Jurkat Cell Line
Item number: BPS-60621
The NFAT Reporter - Jurkat Cell Line contains a firefly luciferase gene under the control of the NFAT response element stably integrated into Jurkat cells. This cell line has been validated for response to thapsigargin, ionomycin, and phorbol 12-myristate 13-acetate (PMA). It is useful as a control cell line for...
| Keywords: | Nuclear factor of activated T cells, T cell, |
| Application: | Intracellular calcium level monitoring, activator / inhibitor / TCR agonist / antagonist screening |
| Species reactivity: | human |
3,268.00€
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WM266-4 Viable Cells
Item number: WM266-4-01-0001
Cells are sterile, validated by short tandem repeat profiling, and are tested as negative for mycoplasma. It is recommended that cell lines are tested for mycoplasma contamination and short tandem repeat (STR) profiling every 10 passages or each time a frozen seed stock is made. See cell culture protocol for...
| Application: | Genetic studies, xenograft production, drug testing, drug target discovery |
| Host: | Human |
| Species reactivity: | human |
From 1,568.00€
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PD-1/NFAT Reporter - Jurkat Recombinant Cell Line
Item number: BPS-60535
Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human PD-1 (GenBank Accession #NM_005018).
| Keywords: | Programmed cell death 1, PDCD1, PD-1, PD1, SLEB2, CD279, HPD-L, PD1/NFAT, PD-1 NFAT, PD-1/NFAT, |
| Application: | Activator / inhibitor screening, PD-1 biological activity characterization |
| Host: | human cells |
| Species reactivity: | human |
13,779.00€
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