tetranor-PGDM ELISA Kit

tetranor-PGDM is a major metabolite of prostaglandin D2 (PGD2) found in human and mouse urine. In human urine, tetranor-PGDM is significantly more abundant than the PGD2 metabolites 11beta-PGF2alpha and 2,3-dinor-11beta-PGF2alpha and is the only endogenous PGD2 metabolite detectable in mouse urine by LC-MS. Normal levels of tetranor-PGDM in human and mouse urine are 1.5 ng/mg creatinine and 8.1 ng/mg creatinine respectively. Cayman's tetranor-PGDM ELISA Kit is a competitive assay that can be used for quantification of tetranor-PGDM in urine. This assay converts tetranor-PGDM to a stable derivative, tetranor-PGJM, that can be easily quantified. The assay has a range from 6.4-4,000 pg/ml and a sensitivity (80% B/B0) of approximately 40 pg/ml.Synonyms: tetranor-PGD Metabolite, tetranor-Prostaglandin D Metabolite EIA Kit. Assay Range: 6.4-4,000 pg/ml. Sensitivity: 80% B/B0: 40 pg/ml. Mid-point: 50% B/B0: 125-250 pg/ml. Cross Reactivity: (tetranor-PGDM) 100%, (tetranor-PGJM) 100%, (tetranor-PGAM) 2.08%, (tetranor-PGEM) 0.03%, (tetranor-PGFM) <0.01%, (Prostaglandin A2) <0.01%, (Prostaglandin D2) <0.01%, (13,14-dihydro-15-keto Prostaglandin D2) <0.01%, (Prostaglandin E2) <0.01%, (13,14-dihydro-15-keto Prostaglandin E2) <0.01%, (Prostaglandin F2alpha) <0.01%, (13,14-dihydro-15-keto Prostaglandin F2alpha) <0.01%, (Prostaglandin J2) <0.01%. Origin: Animal/Eel, Animal/Rabbit, Animal/Bovine, Animal/Mouse.