NIPA (Phospho-Ser354) Colorimetric Cell-Based ELISA Kit

NIPA (Phospho-Ser354) Colorimetric Cell-Based ELISA Kit

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
G-CBCAB01472.96	96 assays (2 x 96-well microplates)		-	-	9 - 20 business days*		641.00€

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NIPA (Phospho-Ser354) Colorimetric Cell-Based ELISA Kit Protein function: Essential component of... more

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Product information "NIPA (Phospho-Ser354) Colorimetric Cell-Based ELISA Kit"

NIPA (Phospho-Ser354) Colorimetric Cell-Based ELISA Kit Protein function: Essential component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events. [The UniProt Consortium]

Keywords:	NIPA, hNIPA, ZC3HC1, HSPC216, Zinc finger C3HC-type protein 1, Nuclear-interacting partner of ALK, Nuclear-interacting partner of anaplastic lymphoma kinase
Supplier:	Assay Genie
Supplier-Nr:	CBCAB01472