MS Mouse KIM-1 (Kidney Injury Molecule 1) ELISA Kit

This ELISA kit applies to the in vitro quantitative determination of Mouse KIM-1 concentrations in serum, plasma and other biological fluids. Photometric. Detection Range: 31.25~2000pg/mL. Sensitivity: 18.75pg/mL. Protein function: Phosphatidylserine receptor that plays an important functional role in regulatory B-cells homeostasis including generation, expansion and suppressor functions (PubMed:21821911, PubMed:25645598, PubMed:32668241). As P-selectin/SELPLG ligand, plays a specialized role in activated but not naive T-cell trafficking during inflammatory responses (PubMed:24703780). Controls thereby T-cell accumulation in the inflamed central nervous system (CNS) and the induction of autoimmune disease (PubMed:24703780). Regulates also expression of various anti-inflammatory cytokines and co-inhibitory ligands including IL10 (PubMed:25582854, PubMed:25645598). Acts as regulator of T-cell proliferation (PubMed:15793576). May play a role in kidney injury and repair. [The UniProt Consortium] Assay Time: 3.5h. Tested Sample Types: Serum, plasma and other biological fluids