Mouse histon-H2b ELISA Kit

The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of histon-H2b in serum, plasma and other biological fluids. Detection Range: 0.39--25ng/mL. Sensitivity: 0.23ng/mL. Protein function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [The UniProt Consortium]