Human DNase-I (Deoxyribonuclease I) ELISA Kit
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-HUES02950.96 | 96 assays | - |
9 - 20 business days* |
534.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
ELISA Type: Sandwich. Sensitivity: 0.094ng/mL. Range: 0.156--10ng/mL. Protein function: Serum... more
Product information "Human DNase-I (Deoxyribonuclease I) ELISA Kit"
ELISA Type: Sandwich. Sensitivity: 0.094ng/mL. Range: 0.156--10ng/mL. Protein function: Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs (PubMed:2251263, PubMed:11241278, PubMed:2277032). Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA. Among other functions, seems to be involved in cell death by apoptosis (PubMed:11241278). Binds specifically to G-actin and blocks actin polymerization. Together with DNASE1L3, plays a key role in degrading neutrophil extracellular traps (NETs). NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation. Degradation of intravascular NETs by DNASE1 and DNASE1L3 is required to prevent formation of clots that obstruct blood vessels and cause organ damage following inflammation. [The UniProt Consortium]
| Keywords: | DNL1, DNase I, Dornase alfa, Deoxyribonuclease-1, Deoxyribonuclease I |
| Supplier: | Assay Genie |
| Supplier-Nr: | HUES02950 |
Properties
| Application: | Sandwich ELISA |
| Species reactivity: | human |
| Format: | Solid Phase |
Database Information
| KEGG ID : | K11994 | Matching products |
| UniProt ID : | P24855 | Matching products |
| Gene ID | GeneID 1773 | Matching products |
Handling & Safety
| Storage: | vT |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319 |
| P Phrases: | P264, P280 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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