Human CUBN (Cubilin) ELISA Kit 

Human CUBN (Cubilin) ELISA Kit 
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-HUES03327.96 96 assays -

9 - 20 business days*

641.00€
 
ELISA Type: Sandwich. Sensitivity: 0.469ng/mL . Range: 0.781--50ng/mL . Protein function:... more
Product information "Human CUBN (Cubilin) ELISA Kit "
ELISA Type: Sandwich. Sensitivity: 0.469ng/mL . Range: 0.781--50ng/mL . Protein function: Endocytic receptor which plays a role in lipoprotein, vitamin and iron metabolism by facilitating their uptake (PubMed:9572993, PubMed:10371504, PubMed:11717447, PubMed:11606717, PubMed:14576052). Acts together with LRP2 to mediate endocytosis of high-density lipoproteins, GC, hemoglobin, ALB, TF and SCGB1A1. Acts together with AMN to mediate endocytosis of the CBLIF-cobalamin complex (PubMed:9572993, PubMed:14576052). Binds to ALB, MB, Kappa and lambda- light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the CBLIF-cobalamin complex. Ligand binding requires calcium (PubMed:9572993). Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol. Binds to LGALS3 at the maternal-fetal interface. [The UniProt Consortium]
Keywords: CUBN, IFCR, Cubilin, 460 kDa receptor, Intrinsic factor-cobalamin receptor, Intestinal intrinsic factor receptor, Intrinsic factor-vitamin B12 receptor
Supplier: Assay Genie
Supplier-Nr: HUES03327

Properties

Application: Sandwich ELISA
Species reactivity: human
Format: Solid Phase

Handling & Safety

Storage: vT
Shipping: +4°C (International: +4°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319
P Phrases: P264, P280
Caution
Our products are for laboratory research use only: Not for administration to humans!
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