hnRNP C1/2 (Phospho-Ser260) Colorimetric Cell-Based ELISA Kit

Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-CBCAB01449.96 96 assays (2 x 96-well microplates) - -

9 - 20 business days*

641.00€
 
hnRNP C1/2 (Phospho-Ser260) Colorimetric Cell-Based ELISA Kit Protein function: Binds pre-mRNA... more
Product information "hnRNP C1/2 (Phospho-Ser260) Colorimetric Cell-Based ELISA Kit"
hnRNP C1/2 (Phospho-Ser260) Colorimetric Cell-Based ELISA Kit Protein function: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles (PubMed:8264621). Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules (PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621). Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides (PubMed:8264621). May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilitating binding of HNRNPC, leading to regulation of mRNA splicing (PubMed:25719671). [The UniProt Consortium]
Keywords: HNRPC, HNRNPC, hnRNP C1/C2, Heterogeneous nuclear ribonucleoproteins C1/C2
Supplier: Assay Genie
Supplier-Nr: CBCAB01449

Properties

Application: In-cell ELISA

Database Information

KEGG ID : K12884 | Matching products
UniProt ID : P07910 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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